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| Product Name | EPZ 004777 |
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| Description | Highly potent DOT1L inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for DOT1L over a panel of other methyltransferases. Selectively inhibits proliferation and induces apoptosis of MLL-rearranged cells in vitro. Prolongs survival in a MLL xenograft mouse model. Purity 98%. MW (observed): 539.67 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
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| Gene, Accession, CAS # | CAS: 1338466-77-5 |
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| Catalog # | 5567/10 |
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| Price | |
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| Order / More Info | EPZ 004777 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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