| 产品详情 |
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| Product Name | AX 15836 |
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| Description | Potent and selective ERK5 inhibitor (IC50 = 8 nM). Exhibits >1,000-fold selectivity for ERK5 over a panel of over 200 kinases. Also exhibits selectivity over bromodomain BRD4 (Kd = 3,600 nM). Increases vomocytosis in human macrophages in vitro, as well as in an in vivo zebrafish model of cryptococcal disease, reducing spread of infection. Purity 98%. MW (observed): 648.78 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5,11-Dihydro-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-methyl,11-(methylsulfonyl)-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one. XMD17-109 |
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| Gene, Accession, CAS # | CAS: 2035509-96-5 |
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| Catalog # | 5843/10 |
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| Price | |
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| Order / More Info | AX 15836 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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