| 产品详情 |
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| Product Name | Axitinib |
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| Description | Potent inhibitor of VEGFR-2, -3, and -1 (IC50 values are 0.2, 0.1-0.3, and 1.2 nM respectively). Exhibits minimal activity against a panel of ~100 protein kinase. Inhibits angiogenesis and vascular permeability. Also a high affinity BCR-ABL1 (T315I) inhibitor (Ki = 149 pM for autophosphorylated ABL1 (T315I)). Blocks proliferation of Ba/F3 cells expressing BCR-ABL1 (T315I). Orally available. Purity 99%. MW (observed): 386.47 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
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| Gene, Accession, CAS # | CAS: 319460-85-0 |
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| Catalog # | 4350/10 |
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| Price | |
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| Order / More Info | Axitinib from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23064517, 23335846, 23963178 |
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| 产品资料 |
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