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Product Name | AZ 10397767 |
Description | Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable. Purity 98%. MW (observed): 400.88 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one |
Gene, Accession, CAS # | CAS: 333742-63-5 |
Catalog # | 5872/50 |
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Order / More Info | AZ 10397767 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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