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| Product Name | AZ 11645373 |
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| Description | Potent and selective human P2X7 antagonist (KB values are 5 - 7 and > 10,000 nM at hP2X7 and rP2X7 respectively) that is completely without effect at all other P2X subtypes. Inhibits BzATP-mediated calcium influx and inhibits ATP-mediated IL-1β release in vitro (KB values are 15 and 92 nM respectively). Purity 98%. MW (observed): 463.51 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione |
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| Gene, Accession, CAS # | CAS: 227088-94-0 |
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| Catalog # | 3317/10 |
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| Price | |
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| Order / More Info | AZ 11645373 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23319734, 24671093, 25938443, 25993132, 26030257, 26877061, 27856358 |
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