产品详情 |
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Product Name | AZ 20 |
Description | Potent and selective ATR kinase inhibitor (IC50 = 5 nM). Exhibits 7.6-fold selectivity over mTOR and selectivity over a panel of 442 kinases, including ATM kinase, PI3-K isoforms, and DNA-PK. Inhibits cell growth in cell lines with high baseline levels of replication stress. Displays antitumor effects in vivo. Purity 98%. MW (observed): 412.51 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole |
Gene, Accession, CAS # | CAS: 1233339-22-4 |
Catalog # | 5198/50 |
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Order / More Info | AZ 20 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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