| 产品详情 |
| Edit |   |
|---|
| Product Name | AZ 3146 |
|---|
| Description | Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases including Cdk1 and aurora kinase B. Interferes with chromosome alignment and overrides spindle assembly checkpoint. Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores. Purity 99%. MW (observed): 452.55 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one |
|---|
| Gene, Accession, CAS # | CAS: 1124329-14-1 |
|---|
| Catalog # | 3994/10 |
|---|
| Price | |
|---|
| Order / More Info | AZ 3146 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 23505430, 26320186, 28607478 |
|---|
| 产品资料 |
|
|