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Product Name | AZD 2098 |
Description | Potent and selective CCR4 antagonist (pIC50 = 7.8). Exhibits no activity at CXCR1 and CXCR2, CCR1, CCR2b, CCR5, CCR7, and CCR8 at 10 μM, and no significant activity when screened against a panel of 120 receptors and enzymes. Inhibits CCL22 Ca2+ response and Th2 cell CCL17/22 driven chemotaxis in vitro. Inhibits lung inflammation following antigen challenge in ovalbumin- sensitized rats. Purity 98%. MW (observed): 334.18 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide |
Gene, Accession, CAS # | CAS: 566203-88-1 |
Catalog # | 6541/10 |
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Order / More Info | AZD 2098 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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