| 产品详情 |
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| Product Name | AZD 2461 |
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| Description | Potent PARP inhibitor (IC50 values are 2, 5 and 200 nM for PARP2, PARP1 and PARP3, respectively). Exhibits anticancer effects in BRCA1 mutant, but not wild-type breast cancer cell lines in vitro. Inhibits growth of olaparib-resistant mammary tumors in a mouse model and is a poor substrate for the P-gp transporter. Orally bioavailable. Purity 98%. MW (observed): 395.43 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone |
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| Gene, Accession, CAS # | CAS: 1174043-16-3 |
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| Catalog # | 6060/10 |
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| Price | |
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| Order / More Info | AZD 2461 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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