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Product Name | AZD 3988 |
Description | Potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable. Purity 98%. MW (observed): 456.44 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | trans-4-[-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid |
Gene, Accession, CAS # | CAS: 892489-52-0 |
Catalog # | 4837/50 |
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Order / More Info | AZD 3988 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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