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Product Name | AZD 7762 hydrochloride |
Description | Potent and selective ATP-competitive inhibitor of Chk1 and Chk2 (IC50 vales are 5 nM for both kinases); displays at least >10 fold selectivity over a panel of 164 kinases. Potentiates cytotoxicity of DNA-damaging agents. Active in vivo. Also improves efficiency of CRISPR-Cpf1-mediated genome editing in hPSC lines (2.7-fold at 1 μM). Purity 98%. MW (observed): 398.88 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide hydrochloride |
Gene, Accession, CAS # | CAS: 1246094-78-9 |
Catalog # | 5199/50 |
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Order / More Info | AZD 7762 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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