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| Product Name | PH 797804 |
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| Description | Potent and selective p38α/β inhibitor (IC50 values are 26 and 102 nM, respectively). Exhibits >100-fold selectivity for p38α/β over 71 other kinases, enzymes and GPCRs, including p38γ, p38δ, JNK and ERK2. Inhibits LPS-induced TNFα production in U937 monocytes in vitro. Suppresses acute and chronic inflammatory responses in rat models of arthritis. Orally active. PH 797804 is the (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer. . Purity 98%. MW (observed): 477.3 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide |
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| Gene, Accession, CAS # | CAS: 1358027-80-1 |
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| Catalog # | 5866/10 |
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| Price | |
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| Order / More Info | PH 797804 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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