产品详情 |
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Product Name | Galiellalactone |
Description | STAT3 inhibitor. Irreversibly binds STAT3 and inhibits binding to DNA. Inhibits IL-6-dependent JAK/STAT signaling. Induces cell-cycle arrest in G2/M phase and apoptosis in androgen-insensitive prostate cancer cells via activation of ATM/ATR pathway. Also destabilizes microtubules and inhibits cell migration. Exhibits anticancer effects in a mouse tumor xenograft model. Purity 95%. MW (observed): 194.23 |
Size | 500 ug |
Concentration | n/a |
Applications | n/a |
Other Names | (4S,5aR,7aR,7bS)-5,5a,6,7,7a,7b-Hexahydro-7b-hydroxy-4-methylindeno[1,7-bc]furan-2(4H)-one |
Gene, Accession, CAS # | CAS: 133613-71-5 |
Catalog # | 6218/500U |
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Order / More Info | Galiellalactone from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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