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| Product Name | SKF 89976A hydrochloride |
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| Description | A potent GABA uptake inhibitor, selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo. Purity 99%. MW (observed): 371.91 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(4,4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride |
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| Gene, Accession, CAS # | CAS: 85375-15-1 |
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| Catalog # | 1081/10 |
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| Order / More Info | SKF 89976A hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20927050 |
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