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| Product Name | SKF 86002 dihydrochloride |
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| Description | Inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 μM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). Also inhibits 5-lipoxygenase- and cyclooxygenase-mediated arachidonic acid metabolism in RBL-1 cells (IC50 values are 10 and 100 μM respectively). Anti-inflammatory following oral administration in vivo. Purity 98%. MW (observed): 370.27 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride |
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| Gene, Accession, CAS # | CAS: 116339-68-5 |
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| Catalog # | 2008/10 |
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| Price | |
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| Order / More Info | SKF 86002 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24244164 |
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