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| Product Name | RN 1734 |
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| Description | Selective TRPV4 antagonist (IC50 values are 2.3, 3.2 and 5.9 μM for hTRPV4, rTRPV4 and mTRPV4 receptors respectively). Displays selectivity for TRPV4 over other TRP channels (IC50 values are 2.3, >30, >30 and >100 μM for TRPV4, TRPV3, TRPM8 and TRPV1 respectively). Blocks TRPV4-mediated arteriole vasodilation and increases myogenic tone ex vivo. MW (observed): 353.31. |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 946387-07-1 |
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| Catalog # | 3746/25 |
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| Order / More Info | RN 1734 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22049072, 22442563, 22492652, 22761937, 23720349, 25739906, 25954200, 26207981, 28886367 |
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