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Product Name | GW 843682X |
Description | Selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). Displays > 100-fold selectivity over ~30 other kinases tested including cdk1 and cdk2. Inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts. Purity 98%. MW (observed): 477.46 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide |
Gene, Accession, CAS # | CAS: 660868-91-7 |
Catalog # | 2977/50 |
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Order / More Info | GW 843682X from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19359241, 20427271, 20962590, 21156286, 21162130, 24205328, 25267294, 26116214, 26685311 |
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