产品详情 |
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Product Name | Pomalidomide |
Description | Potent TNF-α inhibitor (IC50 = 13 nM). Also potently inhibits IL-2 (EC50 = 8 nM). Thalidomide derivative. Binds cereblon and inhibits its ubiquitination. Exhibits antiproliferative effects in a Namalwa lymphoma cell line. Antiangiogenic. Promotes degradation of transcription factor SALL4. Purity 98%. MW (observed): 273.24 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
Gene, Accession, CAS # | CAS: 19171-19-8 |
Catalog # | 6302/10 |
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Order / More Info | Pomalidomide from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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