产品详情 |
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Product Name | Pregnenolone sulfate sodium salt |
Description | Highly potent neurosteroid with multiple actions. Enhances intracellular Ca2+ upon NMDA receptor-mediated synaptic activity (EC50 ~ 2 pM) and potentiates NMDA responses. Inhibitor at GABAA receptors (IC50 values are 0.4 to >300 μM, depending on specific subunit conformation). Activates CREB phosphorylation, augments LTP and cognitive behavior in rat memory models. Also activates TRPM3 channels. MW (observed): 418.52. |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (3β)-3-(Sulfooxy)-pregn-5-en-20-one sodium salt |
Gene, Accession, CAS # | CAS: 1852-38-6 |
Catalog # | 5376/50 |
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Order / More Info | Pregnenolone sulfate sodium salt from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21371490 |
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