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Product Name | PRE-084 hydrochloride |
Description | High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling. Purity 99%. MW (observed): 353.89 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(4-Morpholinethyl) 1-phenylcyclohexanecarboxylate hydrochloride |
Gene, Accession, CAS # | CAS: 138847-85-5 |
Catalog # | 0589/50 |
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Order / More Info | PRE-084 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 14691051, 17522150, 21391983, 22925888, 23494519, 23908387, 24485144, 24599455, 25171370, 25573298, 25926444, 26461475 |
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