| 产品详情 |
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| Product Name | Ciliobrevin A |
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| Description | Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Perturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity. Purity 98%. MW (observed): 358.18 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile. HPI-4 |
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| Gene, Accession, CAS # | CAS: 302803-72-1 |
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| Catalog # | 4529/5 |
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| Price | |
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| Order / More Info | Ciliobrevin A from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26157548, 27334586 |
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