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Product Name | CP 724714 |
Description | Potent and selective ErbB2 inhibitor (IC50 = 10 nM). Exhibits 500-1000-fold selectivity for ErbB2 over ErbB1 and other related RTKs. Induces G1 cell cycle arrest in an ErbB2-overexpressing human cancer cell line. Promotes tumor apoptosis. Induces tumor regression in a human tumor xenograft model. Displays no apparent toxic effect on cardiac tissue. Purity 98%. MW (observed): 469.53 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide |
Gene, Accession, CAS # | CAS: 383432-38-0 |
Catalog # | 5973/10 |
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Order / More Info | CP 724714 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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