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| Product Name | CP 100356 hydrochloride |
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| Description | High affinity P-glycoprotein (P-gp) inhibitor (Ki values are 58 and 94 nM for mouse Pgp1a and Pgp1b isoforms). Inhibits calcein-AM uptake in MDR1-transfected MDCKII cells (IC50 = 0.5 μM) and prazosin transport in BCRP-transfected MDCKII cells (IC50 = 1.5 μM). Displays weak or no inhibitory activity against MRP1, OATP1B1 and several major human P450 enzymes (IC50 > 50 μM). Purity 98%. MW (observed): 597.1 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride |
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| Gene, Accession, CAS # | CAS: 142715-48-8 |
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| Catalog # | 4193/10 |
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| Order / More Info | CP 100356 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26046259 |
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| 产品资料 |
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