| 产品详情 |
| Edit |   |
|---|
| Product Name | PF-06424439 |
|---|
| Description | An orally bioavailable inhibitor of DGAT-2 (IC50 = 14 nM); selective for DGAT-2 over the related acyltransferases DGAT-1, MGAT-2, and MGAT-3 (IC50s = >50 µM); reduces plasma triglyceride levels in sucrose-fed rats in a dose-dependent manner from 0.1-10 mg/kg; reduces plasma levels of cholesterol and triglycerides as well as hepatic triglycerides in LDL receptor knockout mice fed a high-fat, high-cholesterol diet at 60 mg/kg per day |
|---|
| Size | 500 µg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 1469284-78-3 75-75-2 PF06424439 DGAT2 DGAT1 MGAT2 MGAT3 |
|---|
| Gene, Accession, CAS # | CAS: 1469284-79-4 |
|---|
| Catalog # | 17680-500 |
|---|
| Price | |
|---|
| Order / More Info | PF-06424439 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|