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Product Name | NVP 2 |
Description | Potent and selective ATP-competitive CDK9 inhibitor (IC50 = 0.5 nM). Exhibits selectivity for CDK9 over a panel of 468 kinases, but inhibits DYRK1B (IC50 = 350 nM), displays <90% binding to CDK7 (IC50 >10 μM) and CDK13. Inhibits proliferation of MOLT4 cells in vitro. Induces apoptosis. Purity 97%. MW (observed): 513.07 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[[[5'-Chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile |
Gene, Accession, CAS # | CAS: 1263373-43-8 |
Catalog # | 6535/5 |
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Order / More Info | NVP 2 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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