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| Product Name | NVP ADW 742 |
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| Description | ATP-competitive inhibitor of IGF1R (IC50 in the range of 0.1-0.2 μM). Also inhibits c-Kit kinase activity (IC50 in the range of 3-5 μM). Exhibits a synergistic effect with Imatinib, enhancing the sensitivity of multiple small cell lung cancer cell lines to the chemotherapeutics etoposide (Cat. No. 1226) and carboplatin (Cat. No. 2626). Purity 99%. MW (observed): 453.58 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[3-(Phenylmethoxy)phenyl]-7-[trans-3-(1-pyrrolidinylmethyl)cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
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| Gene, Accession, CAS # | CAS: 475488-23-4 |
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| Catalog # | 5247/10 |
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| Price | |
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| Order / More Info | NVP ADW 742 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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