产品详情 |
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Product Name | NVP DPP 728 dihydrochloride |
Description | Potent, orally active dipeptidyl peptidase (DPP)-IV inhibitor (Ki = 11 nM, IC50 = 14 nM) that displays > 15 000-fold selectivity over DPP-II and a range of proline-cleaving proteases. Exhibits antidiabetic activity in vivo; improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, augments insulin secretion and GLUT2 levels, and reduces (preserves) islet size. Purity 97%. MW (observed): 371.27 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile dihydrochloride |
Gene, Accession, CAS # | CAS: 207556-62-5 |
Catalog # | 3506/50 |
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Order / More Info | NVP DPP 728 dihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22821947 |
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