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Product Name | GSK 690693 |
Description | ATP-competitive pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively). Also exhibits some inhibition for AMPK, PKA and PAK and PKC isoforms (IC50 < 100 nM). Displays antiproliferative and apoptotic effects in tumor cell lines. Purity 98%. MW (observed): 425.48 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
Gene, Accession, CAS # | CAS: 937174-76-0 |
Catalog # | 4144/50 |
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Order / More Info | GSK 690693 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22275752, 24243084, 26619345 |
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