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| Product Name | GSK'872 |
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| Description | Potent and selective receptor activating protein kinase 3 (RIP3) inhibitor (IC50 = 1.3 nM). Exhibits >1000-fold selectivity for RIP3 over a panel of 300 other kinases including RIP1. Inhibits TNF-induced cell death in 3T3-SA cells and TLR3-induced necrosis in fibroblasts in vitro. Blocks necroptosis of primary human neutrophils from whole blood. Also induces apoptosis at higher concentrations (3 - 10 μM). Purity 98%. MW (observed): 383.49 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
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| Gene, Accession, CAS # | CAS: 1346546-69-7 |
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| Catalog # | 6492/50 |
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| Price | |
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| Order / More Info | GSK'872 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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