| 产品详情 |
| Edit |   |
| Product Name | VU 0483605 |
| Description | Positive allosteric modulator at mGlu1 (EC50 values are 356 and 390 nM for rat and human receptors, respectively). Exhibits >25-fold selectivity for mGlu1 over mGlu4. Potentiates the decreased glutamate-induced calcium response in mGlu1 mutant cell models of schizophrenia. Purity 98%. MW (observed): 446.67 |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide |
| Gene, Accession, CAS # | CAS: 1623101-11-0 |
| Catalog # | 5377/50 |
| Price | |
| Order / More Info | VU 0483605 from TOCRIS BIOSCIENCE
|
| Product Specific References | PubMed: 29514854 |
| 产品资料 |
|
|