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| Product Name | VU 0360172 hydrochloride |
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| Description | Positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). Selective for mGlu5; displays no significant activity at mGlu1, mGlu2 or mGlu4 receptors. Exhibits antipsychotic-like activity in a rodent model. Also reduces spontaneous spike and wave discharges without affecting motor behaviour in a rat model of absence epilepsy. Purity 98%. MW (observed): 330.78 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide hydrochloride |
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| Gene, Accession, CAS # | CAS: 1309976-62-2 |
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| Catalog # | 4323/10 |
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| Order / More Info | VU 0360172 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 30316834 |
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