| 产品详情 |
| Edit |   |
|---|
| Product Name | Wnt-C59 |
|---|
| Description | Highly potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC50 = 74 pM). Shown to inhibit Wnt signaling pathways. Blocks progression of mammary tumors in MMTV-WNT1 transgenic mice and downregulates Wnt/β-catenin target genes. Induces cardiomyocyte differentiation from human iPSCs following culture with CHIR 99021 (Cat. No. 4423). Cell permeable and orally bioavailable. Purity 99%. MW (observed): 379.45 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide |
|---|
| Gene, Accession, CAS # | CAS: 1243243-89-1 |
|---|
| Catalog # | 5148/10 |
|---|
| Price | |
|---|
| Order / More Info | Wnt-C59 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 28077488, 28523267, 28729840, 28959214 |
|---|
| 产品资料 |
|
|