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| Product Name | Givinostat hydrochloride |
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| Description | Histone deacetylase (HDAC) inhibitor (IC50 = 7.5 to 16 nM). At low concentrations reduces release of pro-inflammatory cytokines, including TNFα, INFγ, IL-1α and IL-1β, from LPS stimulated PBMCs in vitro. Exhibits anti-inflammatory effects in vivo. Improves functional recovery and attenuates tissue damage in a mouse model of traumatic brain injury. Purity 98%. MW (observed): 457.95 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride. ITF 2357 |
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| Gene, Accession, CAS # | CAS: 199657-29-9 |
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| Catalog # | 6249/25 |
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| Order / More Info | Givinostat hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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