| 产品详情 |
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| Product Name | GI 254023X |
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| Description | Selective ADAM10 metalloprotease inhibitor; displays over 100-fold higher potency at ADAM10 compared to ADAM17. Blocks constitutive release of IL-6R, CX3CL1 and CXCL16 in cell-based cleavage experiments. Inhibits calcium ionophore-induced betacellulin shedding in IMPE cells. Prevents E-cadherin cleavage in A549 cells. Inhibits ADAM10 mediated neuronal outgrowth of dorsal root ganglion neurons in vitro. Purity 98%. MW (observed): 391.5 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-2-[(1S)-1-(N-hydroxyformamido)ethyl]-5-phenylpentanamide |
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| Gene, Accession, CAS # | CAS: 260264-93-5 |
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| Catalog # | 3995/1 |
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| Price | |
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| Order / More Info | GI 254023X from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 17895248, 24518602, 25664854, 27043625, 27549131, 28801670 |
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| 产品资料 |
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