| 产品详情 |
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| Antigenic Specificity | PDC_TREM |
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| Clone | 4A6 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-mouse PDC-TREM. PDC-TREM, also known as plasmacytoid dendritic cell (PDC) -specific receptor, is a member of the TREM receptor family. It is a transmembrane protein composed of an extracellular region with one V-type Ig domain, a transmembrane region with a lysine residue, and a cytoplasmic domain with no recognized signaling motifs. The lysine present in the transmembrane region allows PDC-TREM to form a complex with DAP12 and Plexin-A1. PI3K and Erk 1/2 are involved in the signal transduction of this complex. PDC-TREM is expressed in TLR-activated PDCs and is involved in the production of IFN-α. |
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| Immunogen | Recombinant soluble PDC-TREM |
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| Other Names | Plasmacytoid dendritic cell-specific receptor |
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| Gene, Accession # | Gene ID: 328830 |
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| Catalog # | 139203 |
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| Price | |
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| Order / More Info | PDC_TREM Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 23479228 |
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