| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | ERAS |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 1:25, Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ERAS Polyclonal Antibody. The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11. |
|---|
| Immunogen | n/a |
|---|
| Other Names | GTPase ERas, E-Ras, Embryonic stem cell-expressed Ras, Eras |
|---|
| Gene, Accession # | Entrez: 353283; Uniprot: Q7TN89 |
|---|
| Catalog # | PA5-49408 |
|---|
| Price | |
|---|
| Order / More Info | ERAS Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|