| 产品详情 |
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| Antigenic Specificity | CD27 Molecule (CD27) |
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| Clone | LT27 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | PE-DyLight 594 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70. |
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| Immunogen | Human peripheral blood lymphocytes |
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| Other Names | TNFRSF7|S152|Tnfrsf7|Tp55|S152. LPFS2|T14 |
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| Gene, Accession # | Gene ID: 939 |
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| Catalog # | ABIN1111101 |
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| Order / More Info | CD27 Molecule (CD27) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 17937677, 17526459, 9658722, 8241510 |
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