| 产品详情 |
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| Antigenic Specificity | Annexin A5 (ANXA5) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Annexin V, also known as PAP-1 or Lipocortin V, is a ~30 kDa protein that binds to phospholipids in a calcium-dependent manner . All annexins contain a putative PKC binding site, but only annexin V has been identified as an inhibitor of this pathway . It may also signal, by direct interaction with VEGFR2 receptor, in the regulation of vascular endothelial cell proliferation . Annexin V preferentially binds phosphatidylserine, in competition with prothrombin, leading to inhibition of blood coagulation at sites of injury preceding contact between lipid components and coagulation factors that initiate thrombosis . The ability of Annexin V to bind specifically and robustly to phosphatidylserine makes it an attractive reagent in detecting apoptotic cells . Annexin V is inducible by glucocorticoids and can be phosphorylated by tyrosine and serine/threonine kinases . It is thought to block production of mediators of inflammation, such as prostaglandins and leukotrienes by inhibiting the release of arachidonic acid from membranes by phospholipase A2 . Synonyms: ANX5, ENX2, PP4, |
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| Immunogen | Recombinant protein of human ANXA5 |
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| Other Names | anx|anx5|ANX V|anxa5|cb989|wu:fa98f06|wu:fj10f10|MGC89158|ANX5|ENX2|PP4|RPRGL3|Anx5|R74653|LC5|enx2 |
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| Gene, Accession # | Gene ID: 308,11747,25673 |
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| Catalog # | ABIN1683366 |
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| Price | |
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| Order / More Info | Annexin A5 (ANXA5) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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