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| Product Name | Mouse IL-21 Carrier-Free Recombinant Protein |
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| Description | Mouse IL-21 Carrier-Free Recombinant Protein, eBioscience™. IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by Natural Killer Cells (NKT), T helper (Th) 17 and T follicular helper (TFH) cells. In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6. As with IFN gamma for Th1 and IL-4 for Th2 cells, IL-21 is critical for TFH cell development and effector function. IL-21 plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naive B cells. In Th17 cells, IL-21 expression and autocrine feedback through STAT3, I |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Control: Assay-Dependent, Functional Assay: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 60505; Uniprot: Q9ES17 |
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| Catalog # | 34-8211-82 |
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| Price | |
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| Order / More Info | Mouse IL-21 Carrier-Free Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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