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| Product Name | Recombinant Human Serine/threonine-protein kinase PAK 1 |
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| Description | 1-545aa; Full Length. MW: 76.6kD. Purity >90% as determined by SDS-PAGE. Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that link |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Alpha-PAKp21-activated kinase 1; PAK-1p65-PAK] |
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| Gene, Accession, CAS # | PAK1, Gene ID: 5058, Accession: NP_001122092.1 |
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| Catalog # | MBS1467079 |
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| Order / More Info | Recombinant Human Serine/threonine-protein kinase PAK 1 from MYBIOSOURCE INC. |
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| Product Specific References | Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.Brown J.L., Stowers L., Baer M., Trejo J., Coughlin S., Chant J.Curr. Biol. 6:598-605(1996)Human p21-activated kinase (Pak1)regulates actin organization in mammalian cells.Sells M.A., Knaus U.G., Bagrodia S., Ambrose D.M., Bokoch G.M., Chernoff J.Curr. Biol. 7:202-210(1997) Human PAK1B.Reid T., Aspenstroem P., Bertoglio J.Human chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H |
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