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| Product Name | Recombinant Human Serine/threonine-protein kinase PAK 4 |
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| Description | 1-426aa; Full Length of Isoform 2. MW: 63.9kD. Purity >90% as determined by SDS-PAGE. Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates and i |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [p21-activated kinase 4; PAK-4] |
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| Gene, Accession, CAS # | PAK4, Gene ID: 10298, Accession: NP_001014831.1 |
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| Catalog # | MBS1174296 |
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| Order / More Info | Recombinant Human Serine/threonine-protein kinase PAK 4 from MYBIOSOURCE INC. |
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| Product Specific References | PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia.Abo A., Qu J., Cammarano M.S., Dan C., Fritsch A., Baud V., Belisle B., Minden A.EMBO J. 17:6527-6540(1998) Melnick M.B. Characterization of cDNA clones selected by the Gene;Mark analysis from size-fractionated cDNA libraries from human brain.Hirosawa M., Nagase T., Ishikawa K., Kikuno R., Nomura N., Ohara O.DNA Res. 6:329-336(1999) Complete sequencing and character |
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