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| Product Name | PHT 427 |
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| Description | Dual Akt and PDK1 inhibitor; binds the pleckstrin homology (PH) domain of Akt and PDK1 (Ki values are 2.7 and 5.2 μM, respectively). Inhibits Akt phosphorylation and Akt downstream targets; also induces apoptosis in vitro. Displays synergistic antitumor effect when combined with chemotherapeutics in breast cancer mouse models. Purity 98%. MW (observed): 409.61 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-Dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 1191951-57-1 |
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| Catalog # | 4598/50 |
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| Price | |
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| Order / More Info | PHT 427 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20197390 |
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| 产品资料 |
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