| 产品详情 |
| Edit |   |
|---|
| Product Name | AF 12198 |
|---|
| Description | Potent and selective antagonist for the human type I interleukin-1 (IL-1) receptor (IC50 values are 8 nM, > 6.7 mM and > 200 mM for human type I, human type II and murine type I IL-1 receptors respectively). Blocks IL-1-induced expression of ICAM-1 and E-selectin in HUVECs and IL-1β induction of IL-8 in human dermal fibroblasts. Reduces IL-1β-induced IL-6 production and exhibits anti-inflammatory activity in vivo. MW (observed): 1895.14. |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | CAS: 185413-30-3 |
|---|
| Catalog # | 1793/1 |
|---|
| Price | |
|---|
| Order / More Info | AF 12198 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 21151531 |
|---|
| 产品资料 |
|
|