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Product Name | IGF-BP3, human recombinant |
Description | Human IGF-BP3, also known as growth-hormone-dependant binding protein, is a 28.9 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals. In addition to its ability to modulate the activity of IGF-I and IGF-2, IGF-BP3 also exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues. MW: 28.8 kDa. Purity ≥98% |
Size | 1 mg |
Concentration | n/a |
Applications | RUO |
Other Names | Insulin-like Growth Factor-Binding Protein 3, Growth-hormone-dependant binding protein |
Gene, Accession, CAS # | IBP3, Gene ID: 3486, Accession: P17936 |
Catalog # | 4720-1000 |
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Order / More Info | IGF-BP3, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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