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Product Name | IGF-BP5, human recombinant |
Description | Human IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by Vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Studies show that IGF-BP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGF-BP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole body growth inhibition, and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues. MW: 28. 6 kDa. Purity ≥98% |
Size | 100 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Insulin-like Growth Factor-Binding Protein5 |
Gene, Accession, CAS # | IBP5, Gene ID: 3488, Accession: P24593 |
Catalog # | 4723-100 |
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Order / More Info | IGF-BP5, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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