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| Product Name | IGF-BP7, human recombinant |
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| Description | IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Insulin-like growth factor binding protein-7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBPrP1) |
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| Gene, Accession, CAS # | IGFBP7, Gene ID: 3490, Accession: Q16270 |
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| Catalog # | 7167-10 |
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| Order / More Info | IGF-BP7, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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