| 产品详情 |
| Edit |   |
|---|
| Product Name | IGF-BP7, human recombinant |
|---|
| Description | IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Insulin-like growth factor binding protein-7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBPrP1) |
|---|
| Gene, Accession, CAS # | IGFBP7, Gene ID: 3490, Accession: Q16270 |
|---|
| Catalog # | 7167-50 |
|---|
| Price | |
|---|
| Order / More Info | IGF-BP7, human recombinant from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|