| 产品详情 |
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| Antigenic Specificity | CD11a (LFA-1alpha) |
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| Clone | R7.1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD11a (LFA-1alpha) Monoclonal Antibody (R7.1), eBioscience™. CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICA |
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| Immunogen | n/a |
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| Other Names | CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A p180, lymphocyte function-associated antigen 1 alpha polypeptide, integrin alpha-L |
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| Gene, Accession # | Entrez: 3683; Uniprot: P20701 |
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| Catalog # | BMS102 |
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| Price | |
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| Order / More Info | CD11a (LFA-1alpha) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26224111 |
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