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| Product Name | GW 788388 |
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| Description | A selective inhibitor of TGF-β type 1 receptor (TGFBR1 or ALK5; IC50 = 18 nM); inhibits the expression of collagen type I in cells (IC50 = 93 nM) and in mice when given orally at 10 mg/kg once a day; reduces typical features of fibrosis |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1353867-76-1 biochemical inhibitor gene regulation signal transduction receptor biochemistry angiogenesis GW788388 selective inhibition transforming growth factor-β TGF-β TGFβ type 1 TGFBR1 ALK5 TGFBR-1 ALK-5 fibrosis tissue remodeling α-smooth muscle actin fibroblast in vitro signaling hypertrophy femoral growth plate rat collagen I |
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| Gene, Accession, CAS # | CAS: 452342-67-5 |
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| Catalog # | 16255-25 |
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| Price | |
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| Order / More Info | GW 788388 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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