| 产品详情 |
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| Product Name | C2-8 |
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| Description | An inhibitor of polyQ aggregation (IC50s = 25 and 0.05 µM for recombinant HDQ51 and in PC12 cells, respectively); inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington's disease; reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2 transgenic mouse model of Huntington's disease (100 and 200 mg/kg), |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Polyglutamine Aggregation Inhibitor III |
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| Gene, Accession, CAS # | CAS: 300670-16-0 |
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| Catalog # | 21177-1 |
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| Price | |
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| Order / More Info | C2-8 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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